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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea53418c5c843f64ceaf6c3a693ede48ed98ed095937cdb7bff15ec103cce0a' 
  AND token = 'd4ntddzBvbzY0qk89GZ3Zeo4aWo7GiKwBf+/HCPEI/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}