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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6665b1ffeb7ad71dd7896e055d8fa57a59c4c039ff34be89c497469de0bb5f0' 
  AND token = 'T+1lfSz7QoNyGR1wc1eFvwFtxVBOaO47C0YlHMxOcXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}