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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f53f34d2f7fa238e274bf54d82c9101e53321d74c01bf7d39a4a145f5623dd9' 
  AND token = 'tRSyWrSuWGkRWBdTe8Qy1HDdTNlLXU66iN8EI2kbreI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}