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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59eba5cf7092aa3753449eb5049d6d984d4a047bff5831b5465c5f8da43ce19a' 
  AND token = 'BWk5GcyQ3/NX+AuU12B55wNkIJM/qfa3YyjfIl3VE6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}