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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6cd88da7c9b9d0c414361ebfa21a1c136804278d1add8c80990629aaa8fa0b' 
  AND token = 'K8vNcUkOjC+gLxdXSzCnxt+z4b6wIkdiDfJU2CUujdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}