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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '345e9f392815a9b448a7d747517f6527f19a0bb9fedd541f0a7521d82fb73aea' 
  AND token = 'z8XwxF95Ma263fQ6yht2fWTBgCw3npbY4VWKZH6DTUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}