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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec16ae675eee24d1c3faa7b488cc6e239ebfc44d59b6ff57612085d424541a80' 
  AND token = '3N9C9zvFQtaiwkYYKbKVdgdnhXnAVcNHYMYKXRt32Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}