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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f03cebd63e6f81715322ea4e86c7648e8e7bcec6a5c95984ce1006fc153d63d' 
  AND token = 'F2U7Kmq2tIvIlcAT3CajCiY4HvfVVp96smC1ufwKFHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}