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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e2252a37dc35450d8f76e211b1ff81c11f548510c31ea2bc1d0ca03cac424d' 
  AND token = '0f8ur6auLxx4HgpYyNRAK5RVsgIYEsE3XejVqImhtuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}