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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ceac56918896e420a3efa24ab076f6f6e42bc23824f1af9378c7898130e8d70' 
  AND token = 'rJMvNcTY4AYX28JUxDOeWpzkvUta09mwK5zanidU+OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}