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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c741944d9b091a889c4e79c4a89376cb830fa022152c2fff680d71b09b391db8' 
  AND token = 'nb2nqU7ZT1Ipx/xo8TIQdsFxRWRwQWGIOzXDu5ABzM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}