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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f428e0e6b38517ab9480afae7d40256860f6188cf3dc2b6d3f39660d8c308866' 
  AND token = 'V229GeBcJ2EUdcwtbCgWW2iTAFRtotB6oRdQw3Zgx2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}