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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99bb4f53c1a47e833e075762c79c3b9d77053a64546d309fa1d1b169b943763d' 
  AND token = 'X/eo2YBFPe40zHkPDp2GKKTS4fR5KeyXH7qdPZfVuyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}