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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46634da845c45128753a3abff9f1d2cd12cf55cef897dfa51faee5fe9e4f5122' 
  AND token = 'ssqsm8lDvZzogIg18IVKFljaBk5hUTBjyMRr4VZID3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}