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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e817701360e86d3b4ff1ab68adf34272d04a007b6e6fd6f1a8e53f73b065bf9' 
  AND token = '8TRAHzqnD7M2eDUFk1XyhntVSNL/sf4LfydMT49c9BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}