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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4617e6a38760cc1987fc5543fee2a5de79acbd66d1500f31bc7c1da07c4a94a9' 
  AND token = 'G0nYI95lhLd74+hMsS1ph3ZCfH8Xx/WxmT6Y+mSIP9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}