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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dac630233294a2d33b99677a97e079f3765fb17979a3812a6ad8c7a75e521537' 
  AND token = 'HuzV1SByjumj3a0y2tLe00LnSMiwcl5yVzUHuPjpKp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}