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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644d135e3cf2c60c650572dc5e42e775c1ded7d539fc54413b65a3bd8b5e0bf4' 
  AND token = '+Y7h+u9pxXcrwJsHYUc17fCVdRQnrdXDyBqI06WB0OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}