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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '511787dfca5567990c82fe795c4b1cbae04a3e076823653e8c44f3277955bc80' 
  AND token = 'LTllo3+0Xls4dwvwDklxfpgDDDBk3FZty7iKwJCE5bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}