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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ffa6786f20b92cfbc9b756be7f6406dcc72394d535a2559e6004775babf7da' 
  AND token = 'W7p18uPpQfPFLBgsPi3rGKY0Gc3SS3cUep4UUQ2uTEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}