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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22b0b764a14c17014ed541e04c406d690f61592fb02ea700bd5d6bca89d6d69' 
  AND token = 'EdbfOBF/al+mQziUDoXfRRMh0m9ODlJ0ptEMGD3QTf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}