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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9aa8ba82d33dc6f128e6820cd6818a9804a27e6127e15589ef6bfbdbd7704a' 
  AND token = 'bQDwoXYY2bciiubUqAF5cPKfmbQMFAf0qjdmiaK2fHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}