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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a52ef21d356d5caf92bdec4ea3c6d677a4b02918c3f528a82e59edd7ca9e64e' 
  AND token = '0xmQ86ERaRyghVIV52QgyH/UJPQLjdmyyFzL4rUpZJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}