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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b7cbe20aa77486625c039ba222ceedd47520dcd29d1d04eea7ee5546847e8aa' 
  AND token = 'Fx2nCV2MiejQD5ouRrWEKLEQHwBFO1okultW+shK0uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}