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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8a73cad113dd8f7de1f568b3b244024378c1f32bc846f2ad099c3a7b74ca28' 
  AND token = 'yM9Ahq0yhvMrMY2GCzrNUIW1AUXId/xwKRue6KKRo4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}