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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b053ab9e116e1635bd148abe42cc2033b2e7ede5068bba60b16f99808b4e65f6' 
  AND token = 'uekd5xWLQ4rr01pgTogNY8IHMfpq0H8nEkrkMz8aNFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}