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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b266e1da9931994260f42b26cba5f3b7acbd3943d47144a028289cdce2a9c0' 
  AND token = '70dc/bw7hkq1yakKVgWbFBZDWGH8B7PoLUURaX7WFF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}