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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58c3b3cc54f5057aed4c7c293643d9b2eeafee949abf7480a6339b246056a957' 
  AND token = 'l5v1BzAA2N1Ofnxr34tYcw1o2tTRJTDsbfjA+bzXXXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}