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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c5ebb89fd4b93df859301563d0c31a104d7bc5a989b2724ede1733aae2e1a74' 
  AND token = 'Axq0HpX8fEe7TlWPhuEtzWAN6O9yiBZUINubR5jyY0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}