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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af80a60d395afc13dcec73b01b3e697021f8ca7a2644a559a08c47be7e6e4013' 
  AND token = 'lQcvM+aH2jAa5bxmYV9Ki3FEZ7gwflyzZVDRTe8f90Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}