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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0949ff516da401c7d7c1f2b71958a1a658b324f5939c3f26fff0f732b943432' 
  AND token = 'I8pZ765K9wIYTdwsWzM5QqzIwdZ7Jb45Stpna8aOF44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}