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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ceb218e48576673f4d4c1f1c3267977ca7181a0c673af456b60b29ae73d7a27' 
  AND token = 'OlMOoeWAR+Kb0+E+ZI1g+oJvWXn3ot0oBGZhURjUgMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}