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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ae95ed1b73219a2268c5cd43d01ceacfa20371c98e38773eb11a5a780d9b59' 
  AND token = 'gJEIMwMIC/VLk0kwRGFtKQ9lN7K0GptzWY9AXFnHPLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}