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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e294b1c256a8912745e285810a7a54fe10cfae5a670b4934d9bcd3d5a93f36d4' 
  AND token = '2nqws9ATplVl3cJ0eiaaUH0IesUUknC81XuFykK/NNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}