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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6844e2bcd87228b0a6b42022a1a6fb27d8086f8d9c01fbc8c7da5d61d11f30d6' 
  AND token = 'MswDxxMiFnC43/pUifyMUJww8KjRFgbd+AodjjbHqQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}