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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2facc64a7ec1acde85401f3a466b94bf04c23883c828e83f8f2066601659c77' 
  AND token = 'k6QV80UyLOvoynMHqfjy3bC9JWGNOB3vZ16/BdgKo2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}