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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b40a81acaea5827e634a33c33fd04a5304aebea9242d45fc662ff3156e2b129' 
  AND token = 'zwaspWT1/R8GcCGiZQYV4W46/RW/rHbtQ4p+ryD7s2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}