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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4868ed575100c0e2a3fc701d26e0f339b5fda7479c1c9c598710c72d2388010' 
  AND token = 'iRne1TiZoU1V9oc6qxfUKm9vF4BXxLxo/r4jxDTOXA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}