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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dce3370c957dd120b2d252ac7b5c98db131101485bd9afcfe3d2e0bc21e1d4a' 
  AND token = 'qaxMk6zV5G2pBDp0+oo4/qjKfBKwYulNe4S5ipKhQpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}