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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b80b642ed9f70e5b148ca25eb45eac52c63c5240d73b2caacd57395efd4d9707' 
  AND token = 'DSeh87Ax7lwo4oj3LzpZlIXSGpBOP6RjcIqyZP/bYPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}