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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c451f39fc1a677e2c5725088d7f19fc0ae3d2c323132e8eb95d31d1c08b399db' 
  AND token = '3FV+Pxr0FvZyUxBe9CHhc7vgYrytqCrJCFw3PcumvrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}