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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '738cba55eb44062f0de6d9facfce761bd53562ab376ae79e8c1e974f0546af65' 
  AND token = 'x7XO21W7uw3iv2f4AxWUaAPeLpKx2exB9IsaayDauwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}