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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8ba7750bd14554ec3911a44edad8d9f102916ab685cfd6048c87f0c5380fcc' 
  AND token = 'RJwQiMlrUa6tpn0OOcb7rSvkFtF7fVh5VBOxf/lkm9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}