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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77cdc178d9ed808cd886d5f2cc80334db4b883d831daa85b4d2d086ff5b60239' 
  AND token = 'FoPtusEvbMCagTYObOrF2W0/Z4I+DoUu3QfFLpDL1iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}