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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19bd197c8d765d1862c130402aba0b4849b59cf6c10a1c4f208626bcc41374bf' 
  AND token = 'gLk/TodMAEFNDnSHl7lSXqPomk4XAaIopGI0W45RGcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}