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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b4aaa5becd157e5ab8eaccd95fec6324bef517c258e2072bb532c8fe81c9159' 
  AND token = '6ERlm6xKJbOJA6hn49rYSo0CUHppFiqrbkkP2b8uTyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}