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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7f86ff60354843a2be3eaa2b17fe378e9713793d0ecae87e67a3a5ae9dbc42' 
  AND token = 'zOgceKDnbo1UQGq0WU+8kGsreWWw5CJV8s9Dv3V8tX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}