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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4c9f08918950b3ba936395e555c5a2ae723e8ed2b98057798a386ff9a605501' 
  AND token = 'hN2nD0wWDubS45Ku/wZ4xM4+ZiCaxxgKZmJFhVxc8vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}