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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea17ca4b3a89863f451a71933f3cf35bf47b1acd7b1ab1e2521e358d454bc41' 
  AND token = 'TvraWgPO0LbungwWPpNCfgkhLQjpyAw0qFA5V+9ChhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}