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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5133b6e2e3d8121da0741eb0107a6109c39527f2b814e2563fc6e86d8552df1a' 
  AND token = '+e6EpjXi9ATaiS82HLZ993ciLFtCPRJ03V6z/g3J11M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}